During sedation, if stomach contents remain, they can be inhaled into the lungs
Ocular complications have also been reported in some cases
Dont be a drug alternative, be an off-ramp solution/partner. Areas of opportunity include supporting increased resting metabolic rate, exercise tolerance, endurance, muscle and bone health, appetite regulation, satiety and micronutrient sufficiency, as well as addressing hormonal, liver, gut, sleep and baseline nutritional issues that can also impair metabolic health
357 IR in adipose tissue leads to high FFAs levels, 358 visceral fat accumulation that is associated with elevated levels of plasminogen activator inhibitor 1 (PAI-1) and BP, 359 and ectopic lipid and toxic lipid metabolite accumulation (lipotoxicity) in blood vessels that alters cellular signaling and cardiac structure, thereby contributing to the increased prevalence of cardiovascular diseases
The ACHIEVE program for type 2 diabetes includes ACHIEVE-1 (NCT05971940, completed), ACHIEVE-2 (NCT06192108, completed), ACHIEVE-3 (NCT06045221, completed), ACHIEVE-4 (NCT05803421), ACHIEVE-5 (NCT06109311, completed), and ACHIEVE-J (NCT06010004, Japan-specific)